Main Protagonists[]
- Hitomi Kanzaki - The girl from the Mystic Moon
- Van Fanel - King of Fanelia; pilot of Escaflowne
- Merle - Van's childhood friend
- Allen Schezar - The Knight Caeli; pilot of Scherazade
- Millerna Aston - Third Princess of Asturia
- Dryden Fassa - The "Humble" Merchant
Main Antagonists[]
- Dilandau Albatou - Commander of the Dragonslayers
- Folken Fanel (Strategos) - The Zaibach Empire's strategist and Van's older brother
- Emperor Dornkirk - Emperor of Zaibach
- Naria - Pilot of Silver Teiring
- Eriya - Pilot of Gold Teiring
- The Dragonslayers - The squad of elite soldiers led by Dilandau
Minor/Recurring Characters[]
- Susumu Amano - Hitomi's crush
- Yukari Uchida - Hitomi's best friend
- King Grava Aston - King of Asturia
- Meiden Fassa - Merchant and Advisor to King Aston; father to Dryden
- Marlene Aston - First Princess of Asturia; Duchess of Freid
- Eries Aston - Second Princess of Asturia
- Varie Fanel - The Queen of Fanelia
- Goau Fanel - The King of Fanelia
- Mole Man - Mysteriously helpful
- Gaddes - Allen's loyal lieutenant
- Duke Freid - Father of Chid, husband to Marlene
- Chid Freid - Duke Freid and Marlene's son, heir to the Duchy of Freid